Apologies for the vagueness Freya, I suppose this is a reflection of the stage at which I am at within my research. I realise that my question was open ended, I suppose I was hoping for a varied response.
But to answer your questions;
Yes, changes compared to shooting both HD and 2K. I am specifically interested in how shooting in 4K changes for the operation of the camera, rather than the scope that this gives one in post. For example, today I listened to a podcast by the BBC on the topic of what 4K means for production companies, and during this they mentioned that operations such as handheld would have to be more carefully considered due to this translating to a more obvious jitter/shake.
Consequently, the company in question mentioned how they had to replace a few handheld shots for stabalisation; track, larger steadi-cam, jib etc.
Satsuki and Stuart, thank-you very much for your responses. One of the aspects that I am trying to investigate, is whether such digital cropping, and other post benefits, has a consequence in the sense that framing is now easier for the operator (and, dare I say it, requires less talent - especially for a novice), or whether it is simply another tool in the toolkit.
I understand that my questions may have obvious answers, and I'm sure I could predict them, but I would like to hear your viewpoints.
Thanks again!