Rule of thumb, flat, soft frontal source on female talent is often the most flattering as it minimizes shadows on the face. Male talent can be lit more "sidey" as emphasized harsher shadows can convey masculinity as it highlights facial features.
I'd light with one of your soft boxes you mentioned directly frontal and throw a 4x4 of 1/4 or 1/2 white diffusion in front of it. Flag the light if you'd like to increase fall off (depending on your background)
Oh and a good MUA is critical to have.